TBI Centers of Excellence - National Processing Center

A State of the Art Processing Facility

TBI’s National Processing Center (NPC) is based in San Rafael, California and is the central processing facility for all of TBI’s musculoskeletal and skin allografts.  The NPC was established in 1968 and today provides allografts for nearly 100,000 surgeries each year.
Tissue from across the country arrives at NPC to be screened for suitability and prepared for transplant.  NPC provides:

Technology at NPC

TBI continues to look for scientifically based methods to improve allograft quality and patient outcomes.  Our highly-trained Research and Development team continually evaluates existing allografts and designs new, innovative allografts to better meet patient needs.

Innovation is evident in TBI’s pioneering use of Computer Numerically Controlled (CNC) robotic machining technology, which allows our staff to produce allografts with a very high degree of accuracy and precision.  Using proprietary technology and equipment (patents pending), NPC staff produce allografts that are consistent in safety and quality.  These allografts fit easily with surgical instruments, which reduces graft preparation time and makes procedures easier and outcomes more predictable for surgeons and patients.

Another area where NPC leads the way is in the use of irradiation to promote allograft safety.  All allografts prepared at NPC (except burn skin) are terminally sterilized by gamma irradiation which renders them sterile, in accordance with ISO standards.  TBI uses highly controlled radiation dose with low, controlled temperatures using a specialized, validated process.  Each batch is carefully monitored, which allows TBI to keep the dose as low as possible to reduce allograft damage while still providing assurance that each allograft is sterile.